The purpose of the article is the analysis of the causes of the systemic crisis that hit modern civilization through the description of its main structures, identifying the relationship between its elements, assessments of their heuristic potential. This will open up opportunities for finding ways to resolve this crisis, new directions of civilizational development. Theoretical basis of the research are the systems analysis, socio-philosophical and philosophical-anthropological approaches as well as the analysis of scientific developments in the field of global studies. (...) Originality lies in the fact that this article is the first to show the connection between the main structural elements of human civilization as a system. Change in one of the parameters leads to a change in all the others, together with a change in civilization as a whole. Conclusions. The reason for the deep crisis that hit modern civilization is its imbalance as a system. The most important elements of this system are population size, resources and technology, and the core is consciousness in its individual and collective forms. The perception, processing, and use of information, which is a defining civilizational resource, as well as the stability of the entire system depend on the state of consciousness. Consciousness, based on old, obsolete principles and stereotypes, is unable to cope with the most acute challenges of time. New consciousness, since it is formed, will mark the transition to a new theoretical picture of the world and a model of human behavior, in which people will act, driven by proven knowledge, and not willfulness and prejudice. The idea of forming a productive information environment where the ideas of constructiveness and creative work will dominate rather than consumerism and destruction, as is the case at present, must become the categorical imperative of the new consciousness. (shrink)

The importance of communities in strengthening the ethics of international collaborative research is increasingly highlighted, but there has been much debate about the meaning of the term ‘community’ and its specific normative contribution. We argue that ‘community’ is a contingent concept that plays an important normative role in research through the existence of morally significant interplay between notions of community and individuality. We draw on experience of community engagement in rural Kenya to illustrate two aspects of this interplay: (i) that (...) taking individual informed consent seriously involves understanding and addressing the influence of communities in which individuals’ lives are embedded; (ii) that individual participation can generate risks and benefits for communities as part of the wider implications of research. We further argue that the contingent nature of a community means that defining boundaries is generally a normative process itself, with ethical implications. Community engagement supports the enactment of normative roles; building mutual understanding and trust between researchers and community members have been important goals in Kilifi, requiring a broad range of approaches. Ethical dilemmas are continuously generated as part of these engagement activities, including the risks of perverse outcomes related to existing social relations in communities and conditions of ‘half knowing’ intrinsic to processes of developing new understandings. (shrink)

BackgroundThe potential contribution of community engagement to addressing ethical challenges for international biomedical research is well described, but there is relatively little documented experience of community engagement to inform its development in practice. This paper draws on experiences around community engagement and informed consent during a genetic cohort study in Kenya to contribute to understanding the strengths and challenges of community engagement in supporting ethical research practice, focusing on issues of communication, the role of field workers in 'doing ethics' on (...) the ground and the challenges of community consultation.MethodsThe findings are based on action research methods, including analysis of community engagement documentation and the observations of the authors closely involved in their development and implementation. Qualitative and quantitative content analysis has been used for documentation of staff meetings and trainings, a meeting with 24 community leaders, and 40 large public and 70 small community group meetings. Meeting minutes from a purposive sample of six community representative groups have been analysed using a thematic framework approach.ResultsField workers described challenges around misunderstandings about research, perceived pressure for recruitment and challenges in explaining the study. During consultation, leaders expressed support for the study and screening for sickle cell disease. In community meetings, there was a common interpretation of research as medical care. Concerns centred on unfamiliar procedures. After explanations of study procedures to leaders and community members, few questions were asked about export of samples or the archiving of samples for future research.ConclusionsCommunity engagement enabled researchers to take account of staff and community opinions and issues during the study and adapt messages and methods to address emerging ethical challenges. Field workers conducting informed consent faced complex issues and their understanding, attitudes and communication skills were key influences on ethical practice. Community consultation was a challenging concept to put into practice, illustrating the complexity of assessing information needs and levels of deliberation that are appropriate to a given study. (shrink)

_Purpose._ This article aims to provide a philosophical analysis of disharmonious relations between people in society, to reveal the causes of existing conflicts and to find ways to reduce the manifestations of chaos in human relations._ Theoretical basis _of the article is socio-cultural anthropology, the principles of the unity of the historical and logical, the ascent from the abstract to the concrete, the unity of analysis and synthesis. To solve the tasks set, authors also used the principles of objectivity, systematicity, (...) and comprehensive development._ Originality._ The article goes beyond one-sided views on the relationship between people in society, reveals the causes of existing conflicts from a philosophical perspective and searches for ways to reduce chaosogenic manifestations in society. It is assumed that chaos and order in human relations arise not only due to the contradictory interaction between the fundamental components of the Universe – matter and energy, but also due to a lack of understanding of the laws of information use. Therefore, without the discovery and rational use of the basic laws and principles governing the functioning of information in the Universe, it is impossible to overcome chaos in human relations._ Conclusions._ Given the profound impact of information on human relations, it is possible to help reduce the manifestations of chaos in human relationships. The proper handling of information, along with the rational use of matter and energy, is crucial for overcoming the current state of disharmony and creating a more favourable and orderly future for humanity. Thus, the vector of harmonisation of human relations lies in the plane of comprehensive knowledge of mass-energy and information processes occurring in the Universe, focusing not on subjective, ill-considered short-term goals, but submitting to them for consistent inclusion in these processes. (shrink)

В монографии рассматривается соотношение индивидуальных и универсальных начал в праве как эффективное средство решения многих правовых проблем, как руководство в законодательной и судебной деятельности.

The "mathematization" of knowledge is a historically inevitable process governed by two circumstances. In the first place there is the need for the further extension of knowledge in all areas of human activity, whether it be the study of natural phenomena or the theory of taking decisions in the economic or social sphere. Marx pointed out long ago that a science reaches its highest levels only when it succeeds in making use of mathematics. The second circumstance rendering the process of (...) deepening and broadening the mathematization of knowledge not only necessary but possible lies in the constant development both of mathematics itself and of the technical means broadening the sphere of its application. (shrink)

Purpose. The purpose of the article is the analysis of the reasons and grounds of the crisis in the sphere of meaning-making, as well as searching answers to the questions about the meaning of human life in the contemporary world, which are maximally relevant in connection with the escalation of global problems, revealing the points of convergence between various theoretical positions, evaluation of their heuristic potential. Theoretical basis of the research is the historical-philosophical, comparative and system approaches, as well as (...) the analysis of philosophical insights in the field of global studies. Originality. Originality lies in the fact that this article is the first attempt to conduct comprehensive analysis in the problem of the sense of the Existence as it is presented in the first quarter of the 21st century and to relate it with the modern social situation that is characterized by a complex range of interconnected and interdependent anthropological problems of our time. Authors emphasize that the main reason in the crisis of meaning is that a man has lost touch with his roots, which is wildlife. He has created an artificial structure, civilization to satisfy his needs and finds no way to the transcendental, which is the true House of his being. Conclusions. A human must refuse from false self-conceit concerning his potential omniscience and omnipotence, cease dictating his own rules to the Existence, determine the boundaries of his freedom and try to clearly realize his place in the objective structure of being. The global situation can change for the better only if a dramatic change in the area of meaning-making happens. The decisive force, which may encourage nudging to the positive changes, can be either the free will of people who have realized the criticality of the situation or external natural and social circumstances that will make people reorganize radically. The proper prioritizing, a deep awareness of universal goals and solidarity between people could be the value basis that will become the foundation to find the meaning and create a more favorable future. (shrink)

The structural-parametric synthesis of neural networks of deep learning, in particular convolutional neural networks used in image processing, is considered. The classification of modern architectures of convolutional neural networks is given. It is shown that almost every convolutional neural network, depending on its topology, has unique blocks that determine its essential features, Residual block, Inception module, ResNeXt block. It is stated the problem of structural-parametric synthesis of convolutional neural networks, for the solution of which it is proposed to use a (...) genetic algorithm. The genetic algorithm is used to effectively overcome a large search space: on the one hand, to generate possible topologies of the convolutional neural network, namely the choice of specific blocks and their locations in the structure of the convolutional neural network, and on the other hand to solve the problem of structural-parametric synthesis of convolutional neural network of selected topology. The most significant parameters of the convolutional neural network are determined. An encoding method is proposed that allows to repre- sent each network structure in the form of a string of fixed length in binary format. After that, several standard genetic operations were identified, i.e. selection, mutation and crossover, which eliminate weak individuals of the previous generation and use them to generate competitive ones. An example of solving this problem is given, a database of patients with thyroid disease was used as a training sample. (shrink)

The present revolution in science and technology poses complex tasks in the sphere of management of production, tasks determined by the development of technology and technological communications. The essence of these tasks is determined primarily by objective technological and not by subjective organizational factors. The overall complexity of these tasks depends in the first place on the complexity of the development of production and not on the form of control of production adopted. The complexity of present-day production is such, however, (...) that the total mental capacity of the entire adult population would be insufficient to control it effectively. The solution of the problem lies in raising the productivity of labor in control systems, and this is impossible without employment of modern equipment, above all computers. (shrink)

The struggle for peace and social progress was and remains a strategic policy of the Soviet state. As the General Secretary of the CPSU Central Committee, M.S. Gorbachev, stated it at the Extraordinary March Plenum of the Central Committee, it is now vital to reach agreement "on an immediate end to the arms race—particularly nuclear arms—on earth and the banning of it in space.".

The purpose is to identify common and distinctive features of concepts and methodology of the problem of subject within different discourses, implicitly or explicitly relevant to the definition of "clinical" mode of human existence. The research methodology combines techniques of discourse analysis and basic principles of historical and philosophical studies. Originality of the research lies in definition of the clinical philosophical discourse as a special communicative process, where utterances not only focus on disease syndromes, and reveal phenomenology of inner experience (...) of a pathological self, but also structure a certain type of sociality. Clinical discourse represents the space where the patient is treated not as a subject but as an object of disease. Ontology of clinical discourse prevails over ontology of disease, since its structures determine the notion of disease as such. Categorization of the disease, the idea of disease as a phenomenon subdued to professional authority leads to the idea of the need for patient’s isolation from the natural environment and removing him to special social institutions. The clinicist doctrines share the intention to reduce the patient’s self to its bodily dimension, while ignoring social determinants of psychological deviations. Conclusions of the study are summarized in the following positions: the current clinical discourse is based on the positivist-biological trend in humanitarian knowledge and it is the basis for the production and reproduction of medical and pharmaceutical repressive ideology; criticism of philosophical clinical discourse opens the possibility of overcoming the dominance of purely clinicist discourse; such a transformation is possible only after a paradigm shift in understanding the category of subject. (shrink)

Purpose. The article deals with the problem of mutual perception of individuals, which implies the analysis of the anthropological prerequisites for the study of interpersonal communication. The work emphasizes the need to identify the gnoseological lacuna of the possibility and relevance of knowing someone else’s "I". As well as the need to point out implicit metaphysical attitudes, universal for many worldviews, which are implicitly included in the theory of personal communication. Theoretical basis. The author proceeds from the logical consequences of (...) the evolutionary premise in anthropology. He compares the psychophysical goals of the interpersonal communication task with its ideological theory, monitors the impossibility of the realizing the communication level declared in the consciousness. As an opposite evolutionary premise, the author cites the postulates of the "philosophy of dialogue" by F. Rosenzweig, F. Ebner, M. Buber, and others. The correlation of these philosophical positions reveals the inconsistency of materialistic reduction in anthropology. Originality. The author identifies four levels of communication: background, obstacle, function and dialogue. He represents the rationale for the fact that the first three levels do not need the existence of an individual "I". The first three levels leave the existential "I" unnecessary and therefore unclaimed. The philosophy of dialogue with the Other raises an equally important question about the conditions for the possibility of a metaphysical continuum in ontology, and in turn, suggests the acceptance of a philosophical premise about God as the space of subjectivity in the "I-You" dialogue. Conclusions. Philosophical understanding of the communication of two existential "I" demanded in communication is possible only within the framework of religious discourse. The phenomenal consciousness can enter into communication with a specific other phenomenal consciousness only when there is a metaphysical space between them, allowing for the possibility of communication of such a level. The materialistic conditioning by the human evolutionary needs in all its conceivable forms produces a reduction of the communicative inquiry, which makes the mutual perception of the two "I" impossible. In this psychophysiological anthropological model, there is no space for the possibility of a dialogue of individuals. (shrink)